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Prednisone half life11/27/2023 Ĭhemically, methylprednisolone is a synthetic pregnane steroid hormone derived from hydrocortisone and prednisolone. Serious side effects include iatrogenic Cushing's Syndrome, hypertension, osteoporosis, diabetes, infection, and skin atrophy. It is associated with many adverse reactions that require tapering off the drug as soon as the disease is under control. Regardless of route of administration, methylprednisolone integrates systemically as exhibited by its effectiveness to quickly reduce inflammation during acute flares. Methylprednisolone and its derivatives can be administered orally or parenterally. It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares. ![]() Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects.
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